Chad Huskins is the EVVY Award-winning author of Zero Star and The Sol Ascendancy.
I got inspired recently to write up a list of the opening lines in novels that have stuck out to me be the most. So here they are, in no particular order, with an explanation of why these are so great.
1. "Hither came Conan, the Cimmerian, black-haired, sullen-eyed, sword in hand, a thief, a reaver, a slayer, with gigantic melancholies and gigantic mirth, to tread the jeweled thrones of the Earth under his sandaled feet." - Robert E. Howard, The Phoenix on the Sword (the first Conan story)
This one is famous among fans of the "sword and sorcery" genre. It sets the stage perfectly for the story that is about to unravel, a story told by Howard's brutal imagery, his wondrous worlds, and his driving narrative that revealed barbarism as something potentially redemptive in Man, and not something to be shunned or hated. Howard had a strong belief in the masculine, in the iron will to forge one's own path, as Conan does. This opening line basically says, "Here comes a badass, and you'd do well to get out of his way."
2. "It is a truth universally acknowledged, that a single man in possession of a good fortune, must be in want of a wife." - Jane Austen, Pride & Prejudice
From the masculine, we go to the feminine...and the witty. Like any good opening line should do, Austen's presents a general premise without trying to divulge plot-plot-plot all at once. Some people miss the humor in the opening line, thinking Austen is dead serious. Far from it. She means it in the sense that people have accepted that a single man who is rich must be searching for a wife, particularly in the world she's established. The people in her story (and of the Age she lived in) care for nothing more than to have their daughters married well off, hopefully to the advantage of the rest of the family--i.e., her husband is rich and can help pay everyone's bills.
3. "Call me Ishmael. Some years ago--never mind how long, precisely..." Herman Melville, Moby Dick
Though I don't have the room to thoroughly go through Melville's entire opening, it all stems from this line, which immediately establishes a familiarity between the reader and the narrator. And yet there is also great ambiguity right off the bat, for Melville basically says "Just call me by my first name," doesn't bother with a last name, and then just says "this happened a while back, but it doesn't matter just how long ago." Familiarity coupled with ambiguity...kind of like an old friend you've not seen in a while, returning to tell you about a thing that changed him forever while he was gone. The reader is invited in. We've been invited to the pub, where a lonely man named Ishmael sits, perhaps alone, with ale in hand, to tell us a story. Let's have a seat with him, and hear what he has to say...
4. "It was a bright cold day in April, and the clocks were striking thirteen." - George Orwell, 1984
This one is haunting because...well, we the readers happen to know that that's NOT how clocks work. This begins the story of a world that has gone terribly, terribly wrong. In this book, which famously created the terms "Big Brother" and "double-think," we find ourselves in a world where lies are truth, truth are lies, the government controls the narrative strictly, the freedom of the press has been dismantled, and Big Brother is always watching. If it is not the original dystopian future novel, then it is, without a doubt, the reigning champion by which all others are judged. And from the opening line, we already know that something is wrong...
5. "It was the best of times, it was the worst of times, it was the age of wisdom, it was the age of foolishness, it was the epoch of belief, it was the epoch of incredulity, it was the season of Light, it was the season of Darkness, it was the spring of hope, it was the winter of despair, we had everything before us, we had nothing before us, we were all going direct to Heaven, we were all going direct the other way – in short, the period was so far like the present period, that some of its noisiest authorities insisted on its being received, for good or for evil, in the superlative degree of comparison only." - Charles Dickens, A Tale of Two Cities
Dickens decided to put the reader into the mood of his setting, but, like he says at the end, the "time" he's referring to is EXACTLY like whatever era the reader happens to be in when they're reading it. He suggests that nothing ever changes, in that all times can be described as the worst, or the best, and that people will often describe whatever era they're living in as both. It depends on where you are in life, what privileges or station you have. These things determine how good or bad you view the current era. And, as he says, the "noisiest authorities" seem intent to only be able to make their arguments for their current period being the "best" or "worst" by using comparisons.
6. "The man in black fled across the desert, and the gunslinger followed." - Stephen King, The Gunslinger
This line cuts right to it. It says "Here's your story." Of course, there's still plenty of mystery. We don't know who either of these men are, or why one is chasing the other, but we're immediately fascinated. An old adage among writers is to "Start your story in the middle." Kind of like how the first Star Wars movie begins with us seeing the Rebel starship already being chased by the Imperial ship. We're learning who Darth Vader is while the story is on the move, almost like we came in the middle of a TV series and missed the whole first half. It's an excellent way to get readers invested right away, and have them salivating for the details that explain why these characters are doing what they're doing. Much better than describing them at length at the beginning, and then getting us to the chase around Chapter 4. Stephen King himself has expressed that he believes this opening line is his most solid work.
7. "The most merciful thing in the world, I think, is the inability of the human mind to correlate all its contents." - H.P. Lovecraft, The Call of Cthulu
H.P. Lovecraft is considered by most people to be the greatest horror writer of all time, and he never even wrote about an ax murderer, or described the sight entrails overly long. No, Lovecraft made a career by inventing a new style of writing--he would describe all the things that the "monster" DIDN'T look like, or would be so vague in his description, and yet all the while summoning imagery, that he encourage the reader to think up something even more dreadful on their own, something that defied all known geometry, physics, and biology. The true horror for Lovecraft was the idea that some things might be forever beyond the ken of Man, and what might happen if a human being witnessed, with their own eyes, the things that they were never meant to see? That's what this opening line is all about. Lovecraft would consider it a "mercy" if the human mind could simply go on not understanding all the horrors it had seen...especially after the narrator of this story reveals to you the truth terrors he has witnessed. He wants to forget. More than anything, he wants to be oblivious again. Ignorance is bliss...
Showing posts with label horror. Show all posts
Showing posts with label horror. Show all posts
Monday, February 20, 2017
Thursday, March 10, 2016
ZOMBIE AUTOPSY: How do they work?
For whatever reason, there has been a resurrection (pardon the pun) of interest in zombies over the last decade. Though filmmaker George A. Romero is usually credited with creating our contemporary understanding of zombies with the 1968 classic Night of the Living Dead, tales of zombies have been around since about 1918, and of course stories of general resurrection predate even that, but those are religious tales, the more supernatural kind.
We won't be talking about these zombies. We'll be talking about Romero-style zombies, and/or The Walking Dead-type zombies because, well, I have a lot of questions when it comes to exactly how someone could be technically dead, yet still walk, exhibit enough strength to sometimes rip and tear flesh like a grizzly bear, yet continue to show obvious signs of decay. How could they (conceivably) work?
Submitted for your approval, I present:
The Resurrection Process
All right, so, we'll start from the start. How can a person return from the dead, move about like they're alive, see with their eyes and hear with their ears, yet still have necrosis (decay) taking place in almost all important skin, muscle, and other tissue cells?
As it happens, this has been explored in actual, real-world research before, because, believe it or not, there were supposed zombies in real life in Haiti, at least as far back as 1980, when a man walked into a village and claimed to be Clairvius Narcisse, a man that had died in a hospital in Deschapelles, May 2, 1962. He had memories of Narcisse's life that even close relatives had forgotten. Other Haitian zombies have materialized through the years.
Dr. Wade Davis, an anthropologist and ethnobotanist, conducted extensive research and came to the conclusion that the "Haitian zombie" phenomenon was caused by a rare drug, called tetrododoxin, which comes from the puffer fish. Combined with toxins from a native tree toad and other chemicals, it could be made into a powder that put people so close to death that it was difficult to determine whether or not they were alive. They could also be brought back, and while most suffered long-lasting effects, some fully recovered! But a few returned and, while cognizant, had lost some fine motor skills. This powder could kill someone, yet keep them in a rare state where resurrection was still possible, and place the living in a condition where they lost many motor skills and had only faint life signs (like a zombie).
But zombism is obviously brought on by a pathogen, not a powder. So, from here on, we shall refer to this pathogon as "Z-1" for simplicity's sake.
Virology
Bites from zombies, such as those in The Walking Dead, show that zombism is communicable, and therefore lend more credence that this is a pathogen. It causes tremors and terrible fever. Z-1 probably behaves much like malaria, first hiding within the liver, where it multiplies and grows stronger. Then, once it has marshaled enough forces, it invades the bloodstream, where it infects red blood cells. Now come the symptoms: fever, shivering, anemia, vomiting, and convulsions.
After that, Z-1 obviously shuts down the higher brain functions, but leaves the most basic sensory perceptions. But Z-1 shows how diverse it is by not only affecting brain and motor functions, but also damaging other major tissues separate from the brain.
To attack humans so specifically, and not other animals like dogs and cats, Z-1 is probably either a single- or double-stranded DNA virus. This means it actually has DNA as its genetic material and replicates using DNA-dependent DNA polymerase: an enzyme that acts as a catalyst. Z-1 therefore probably shares a morphology not unlike Herpesvirales (the herpes virus). And, like herpes, you can catch it from a bite.
While a bite clearly accelerates the infection, we are all carrying the Z-1 virus, just as 1/3 of us are carrying tuberculosis around without any ill effects (for the most part). This is why those dead from natural causes or accidents also succumb to Z-1, which indicates that Z-1 is lying in wait for the immune system to "switch off" so it can have its day in the sun.
Necrotic Skin and Bone
Flesh sloughing off, turning blue and gray, and generally remaining damaged long after wounds ought to have scabbed over; all of these indicate that Z-1 has a unique effect on human skin.
Oxygen blockages to skin cells causes necrosis; that's the premature death of cells in living tissue. Necrosis can happen to the living in various ways, including snake and spider bites, which indicates that Z-1 lives very, very well in human saliva, and, like the bite from a brown recluse spider, it begins a slow process of killing tissues. But that doesn't mean it has to kill muscle tissues--only skin and flesh tend to decay, at least initially. When zombies are injured by running into things or getting shot, the wound never heals because skin cells are dead, and the immune system, rocked by the other effects of Z-1, cannot address the problems of infections by other organisms, which only increases decay.
Given enough time, Z-1 causes necrosis of bone cells, which brings on symptoms similar to osteogenesis imperfecta (brittle bone disease), of a Type IV kind or above. In this phase of zombism, bones are easily fractured. This is why "older" zombies (those who've had Z-1 the longest and have gone through all the major cellular breakdown stages) are mushier, easier to hack to pieces, exactly like a corpse.
The Brain
Like many viruses, Z-1 must mutate in order to survive. Otherwise, it would be easy to catch and kill. Therefore, after Z-1 has grown strong in the liver and successfully invaded the bloodstream, it quickly mutates into a whole new strand, known as Z-2, and migrates into the brain to live out the rest of its days.
The fact that zombies can still see means that Z-2 does not have much of an effect on the occipital lobe; the visual cortex. Gray matter in the brain is obviously influenced in a very special way (gray matter controls sensory perception, muscle control, emotions, speech, hearing and memory). A condition known as "gray matter heterotopia" can cause seizures, loss of higher brain functions, and mental retardation. Z-2 imitates these symptoms by "slushing" the brain, causing severe swelling and thus moving portions of gray matter around, exactly as heterotopia does.
Z-2 shuts down most of the brain's other regions. The frontal lobe, which controls the ability to recognize future consequences of current actions, is almost completely shut down. In most sufferers, Z-2 shuts down the parietal lobe, too, which means they cannot manipulate objects at all. However, some zombies do show the ability to figure out simple objects, such as doorknobs, which indicates Z-2 doesn't always attack the parietal lobe so aggressively.
As far as motor functions go, Z-2 initially behaves much like Guillain-Barre Syndrome (GBS). GBS is an acute neuropathy, which is a disorder that affects the peripheral nervous system. In short, you lose control of your limbs. Even after a body recovers from GBS, coordination is extremely difficult, survivors can't run as fast as they did before (at least, not without rehabilitation). This would explain why zombies usually can't run as fast as they did when they were alive, yet can still stand and move about. They've "survived" the first initial shock of Z-2 on their brain, but the communication between brain and muscles has been damaged forever, causing a lack of coordination.
Zombie Strength
Zombies often show that they can pry a person's belly open just with their bare hands. How is this possible?
Well, under extreme circumstances, normal human beings have been known to exhibit incredible strength not thought possible. This phenomenon is called "hysterical strength." (Is there anything more hysterical than a zombie?) Hysterical strength most commonly occurs when someone is single-minded, not caring about the consequences. It also happens to tear muscles and damaged joints: of course, sufferers of Z-2 have lots of damages to their bodies.
The brain (which we covered above) controls everything in the human body, including limiting the number of muscle fibers the body can use at once: this prevents you from overexerting and hurting yourself. The brain also motivates the processes that create lactic acids, which also factor in. Since Z-2 shuts down so much of the brain, it not only leaves the zombie without lactic acid production, it allows a zombie to use its maximum strength (practically every muscle fiber in its entire body) to rip and tear and rend. Jaw muscles are affected, just like everything else, so this gives the zombie the ability to bite so hard it can tear off huge chunks of human flesh in one bite.
This is why, while zombies appear flimsy, clumsy, and sometimes mushy, they can demonstrate incredible power when they've got their hands on a victim.
Insatiable Hunger
Back to the brain for this one. Z-2 obviously affects the hypothalamus region of the brain in a very unique way. There are two parts of the hypothalamus that control eating and hunger. The lateral hypothalamus gives the signal when it's time to start eating, and the ventromedial nucleus gives the signal when it's time to stop eating. Human beings only feel satiated when the ventromedial nucleus is functioning properly. Z-2 sufferers often have this part of their brain operating at such a low level that it's practically dead.
Real-world evidence shows that people who have had their ventromedial nucleus injured are unable to determine when they should stop eating.
Incidentally, this region also helps control fear and sexual activity: the fact that this region of the brain is nearly dead shows just how much humanity Z-2 robs of its victims.
Inhuman Growling
"New" zombies typically only moan or hiss. But over time, necrotic damage to the esophagus and vocal cords cause many zombies to begin pushing wind through nothing more than a leaking pipe. Their throat and lungs begin to fill with liquid, and they are now gurgling more than growling. This creates an unpleasant gurgle/growl in "older" zombies.
However, if their lungs are filled with liquid, we get some interesting questions. How do zombies continue to move when the brain depends on oxygen and blood delivered to it from other parts of the body? How can Z-2 survive in the brain at all, since the brain must surely and eventually die due to asphyxiation and ischemia? That is, without the lungs functioning, or the heart, how does the brain receive air and blood?
The answer: It doesn't.
Z-2 sufferers still take in ample amounts of flesh (human flesh is their favorite), and this provides incredible energy for the brain to continue to function, replacing the need for oxygen and steady bloodflow altogether. Z-2 is therefore not just a virus, but a powerful new agent that transforms the body's normal processes and ultimately serves as a very specialized life-support system for the brain, and the brain alone.
Because of this, Z-2 is able to sustain itself for a very, very long time, as long as it remains in its comfortable "cradle" inside the base of the brain. As long as nerves and connective tissues remain intact, Z-2 can keep the brain going enough to send the basest commands to its limbs.
It is not yet known how long it would take for Z-2 to die on its own.
Origin and Final Analysis
It's possible that Z-1 was manmade, as many have hypothesized. One clue is that, as stated above, it targets the human hypothalamus, making it yearn for sustenance, but does not affect the brains of other animals. And while zombies will feast on other animals if they have to, they obviously prefer a fresh human meal, yet do not often feed on each other. They care not for their fellow dead, they show no sign of loss when one of their own gets shot or decapitated, and they lust only for flesh from the living.
Perhaps Z-1 only makes its victims "dance," makes of them puppets. If not...
If not, then it indicates that when everything else is stripped away, when all pretenses of society and community are removed, and when human beings are laid bare and left with only their basest desires, they have only one craving, one thing that they want more than anything else: the destruction of one another. Not to hug or make love, not to make picnics or hold hands. But to devour that which they hate most. Themselves.
A pathogen that causes humans to target humans. Certainly sounds manmade. Or else, the wrath of Nature.
For a more detailed autopsy, please see below:
Office of the Chief Medical Examiner
Fulton County 2nd District
Atlanta, GA
AUTOPSY REPORT
Male Subject - Daniel William Egleston
Case No. 886670T
Approximate Age: 31 years
Height: 70 inches
Weight: 189.8 lbs.
Sex: Male
We won't be talking about these zombies. We'll be talking about Romero-style zombies, and/or The Walking Dead-type zombies because, well, I have a lot of questions when it comes to exactly how someone could be technically dead, yet still walk, exhibit enough strength to sometimes rip and tear flesh like a grizzly bear, yet continue to show obvious signs of decay. How could they (conceivably) work?
Submitted for your approval, I present:
Zombie Autopsy!
The Resurrection Process
All right, so, we'll start from the start. How can a person return from the dead, move about like they're alive, see with their eyes and hear with their ears, yet still have necrosis (decay) taking place in almost all important skin, muscle, and other tissue cells?
As it happens, this has been explored in actual, real-world research before, because, believe it or not, there were supposed zombies in real life in Haiti, at least as far back as 1980, when a man walked into a village and claimed to be Clairvius Narcisse, a man that had died in a hospital in Deschapelles, May 2, 1962. He had memories of Narcisse's life that even close relatives had forgotten. Other Haitian zombies have materialized through the years.
Dr. Wade Davis, an anthropologist and ethnobotanist, conducted extensive research and came to the conclusion that the "Haitian zombie" phenomenon was caused by a rare drug, called tetrododoxin, which comes from the puffer fish. Combined with toxins from a native tree toad and other chemicals, it could be made into a powder that put people so close to death that it was difficult to determine whether or not they were alive. They could also be brought back, and while most suffered long-lasting effects, some fully recovered! But a few returned and, while cognizant, had lost some fine motor skills. This powder could kill someone, yet keep them in a rare state where resurrection was still possible, and place the living in a condition where they lost many motor skills and had only faint life signs (like a zombie).
But zombism is obviously brought on by a pathogen, not a powder. So, from here on, we shall refer to this pathogon as "Z-1" for simplicity's sake.
Virology
Bites from zombies, such as those in The Walking Dead, show that zombism is communicable, and therefore lend more credence that this is a pathogen. It causes tremors and terrible fever. Z-1 probably behaves much like malaria, first hiding within the liver, where it multiplies and grows stronger. Then, once it has marshaled enough forces, it invades the bloodstream, where it infects red blood cells. Now come the symptoms: fever, shivering, anemia, vomiting, and convulsions.
After that, Z-1 obviously shuts down the higher brain functions, but leaves the most basic sensory perceptions. But Z-1 shows how diverse it is by not only affecting brain and motor functions, but also damaging other major tissues separate from the brain.
To attack humans so specifically, and not other animals like dogs and cats, Z-1 is probably either a single- or double-stranded DNA virus. This means it actually has DNA as its genetic material and replicates using DNA-dependent DNA polymerase: an enzyme that acts as a catalyst. Z-1 therefore probably shares a morphology not unlike Herpesvirales (the herpes virus). And, like herpes, you can catch it from a bite.
While a bite clearly accelerates the infection, we are all carrying the Z-1 virus, just as 1/3 of us are carrying tuberculosis around without any ill effects (for the most part). This is why those dead from natural causes or accidents also succumb to Z-1, which indicates that Z-1 is lying in wait for the immune system to "switch off" so it can have its day in the sun.
Necrotic Skin and Bone
Flesh sloughing off, turning blue and gray, and generally remaining damaged long after wounds ought to have scabbed over; all of these indicate that Z-1 has a unique effect on human skin.
Oxygen blockages to skin cells causes necrosis; that's the premature death of cells in living tissue. Necrosis can happen to the living in various ways, including snake and spider bites, which indicates that Z-1 lives very, very well in human saliva, and, like the bite from a brown recluse spider, it begins a slow process of killing tissues. But that doesn't mean it has to kill muscle tissues--only skin and flesh tend to decay, at least initially. When zombies are injured by running into things or getting shot, the wound never heals because skin cells are dead, and the immune system, rocked by the other effects of Z-1, cannot address the problems of infections by other organisms, which only increases decay.
Given enough time, Z-1 causes necrosis of bone cells, which brings on symptoms similar to osteogenesis imperfecta (brittle bone disease), of a Type IV kind or above. In this phase of zombism, bones are easily fractured. This is why "older" zombies (those who've had Z-1 the longest and have gone through all the major cellular breakdown stages) are mushier, easier to hack to pieces, exactly like a corpse.
The Brain
Like many viruses, Z-1 must mutate in order to survive. Otherwise, it would be easy to catch and kill. Therefore, after Z-1 has grown strong in the liver and successfully invaded the bloodstream, it quickly mutates into a whole new strand, known as Z-2, and migrates into the brain to live out the rest of its days.
The fact that zombies can still see means that Z-2 does not have much of an effect on the occipital lobe; the visual cortex. Gray matter in the brain is obviously influenced in a very special way (gray matter controls sensory perception, muscle control, emotions, speech, hearing and memory). A condition known as "gray matter heterotopia" can cause seizures, loss of higher brain functions, and mental retardation. Z-2 imitates these symptoms by "slushing" the brain, causing severe swelling and thus moving portions of gray matter around, exactly as heterotopia does.
Z-2 shuts down most of the brain's other regions. The frontal lobe, which controls the ability to recognize future consequences of current actions, is almost completely shut down. In most sufferers, Z-2 shuts down the parietal lobe, too, which means they cannot manipulate objects at all. However, some zombies do show the ability to figure out simple objects, such as doorknobs, which indicates Z-2 doesn't always attack the parietal lobe so aggressively.
As far as motor functions go, Z-2 initially behaves much like Guillain-Barre Syndrome (GBS). GBS is an acute neuropathy, which is a disorder that affects the peripheral nervous system. In short, you lose control of your limbs. Even after a body recovers from GBS, coordination is extremely difficult, survivors can't run as fast as they did before (at least, not without rehabilitation). This would explain why zombies usually can't run as fast as they did when they were alive, yet can still stand and move about. They've "survived" the first initial shock of Z-2 on their brain, but the communication between brain and muscles has been damaged forever, causing a lack of coordination.
Zombie Strength
Zombies often show that they can pry a person's belly open just with their bare hands. How is this possible?
Well, under extreme circumstances, normal human beings have been known to exhibit incredible strength not thought possible. This phenomenon is called "hysterical strength." (Is there anything more hysterical than a zombie?) Hysterical strength most commonly occurs when someone is single-minded, not caring about the consequences. It also happens to tear muscles and damaged joints: of course, sufferers of Z-2 have lots of damages to their bodies.
The brain (which we covered above) controls everything in the human body, including limiting the number of muscle fibers the body can use at once: this prevents you from overexerting and hurting yourself. The brain also motivates the processes that create lactic acids, which also factor in. Since Z-2 shuts down so much of the brain, it not only leaves the zombie without lactic acid production, it allows a zombie to use its maximum strength (practically every muscle fiber in its entire body) to rip and tear and rend. Jaw muscles are affected, just like everything else, so this gives the zombie the ability to bite so hard it can tear off huge chunks of human flesh in one bite.
This is why, while zombies appear flimsy, clumsy, and sometimes mushy, they can demonstrate incredible power when they've got their hands on a victim.
Insatiable Hunger
Back to the brain for this one. Z-2 obviously affects the hypothalamus region of the brain in a very unique way. There are two parts of the hypothalamus that control eating and hunger. The lateral hypothalamus gives the signal when it's time to start eating, and the ventromedial nucleus gives the signal when it's time to stop eating. Human beings only feel satiated when the ventromedial nucleus is functioning properly. Z-2 sufferers often have this part of their brain operating at such a low level that it's practically dead.
Real-world evidence shows that people who have had their ventromedial nucleus injured are unable to determine when they should stop eating.
Incidentally, this region also helps control fear and sexual activity: the fact that this region of the brain is nearly dead shows just how much humanity Z-2 robs of its victims.
Inhuman Growling
"New" zombies typically only moan or hiss. But over time, necrotic damage to the esophagus and vocal cords cause many zombies to begin pushing wind through nothing more than a leaking pipe. Their throat and lungs begin to fill with liquid, and they are now gurgling more than growling. This creates an unpleasant gurgle/growl in "older" zombies.
However, if their lungs are filled with liquid, we get some interesting questions. How do zombies continue to move when the brain depends on oxygen and blood delivered to it from other parts of the body? How can Z-2 survive in the brain at all, since the brain must surely and eventually die due to asphyxiation and ischemia? That is, without the lungs functioning, or the heart, how does the brain receive air and blood?
The answer: It doesn't.
Z-2 sufferers still take in ample amounts of flesh (human flesh is their favorite), and this provides incredible energy for the brain to continue to function, replacing the need for oxygen and steady bloodflow altogether. Z-2 is therefore not just a virus, but a powerful new agent that transforms the body's normal processes and ultimately serves as a very specialized life-support system for the brain, and the brain alone.
Because of this, Z-2 is able to sustain itself for a very, very long time, as long as it remains in its comfortable "cradle" inside the base of the brain. As long as nerves and connective tissues remain intact, Z-2 can keep the brain going enough to send the basest commands to its limbs.
It is not yet known how long it would take for Z-2 to die on its own.
Origin and Final Analysis
It's possible that Z-1 was manmade, as many have hypothesized. One clue is that, as stated above, it targets the human hypothalamus, making it yearn for sustenance, but does not affect the brains of other animals. And while zombies will feast on other animals if they have to, they obviously prefer a fresh human meal, yet do not often feed on each other. They care not for their fellow dead, they show no sign of loss when one of their own gets shot or decapitated, and they lust only for flesh from the living.
Perhaps Z-1 only makes its victims "dance," makes of them puppets. If not...
If not, then it indicates that when everything else is stripped away, when all pretenses of society and community are removed, and when human beings are laid bare and left with only their basest desires, they have only one craving, one thing that they want more than anything else: the destruction of one another. Not to hug or make love, not to make picnics or hold hands. But to devour that which they hate most. Themselves.
A pathogen that causes humans to target humans. Certainly sounds manmade. Or else, the wrath of Nature.
For a more detailed autopsy, please see below:
Autopsy of Z-1 Sufferer
-------------------------------
Office of the Chief Medical Examiner
Fulton County 2nd District
Atlanta, GA
AUTOPSY REPORT
Male Subject - Daniel William Egleston
Case No. 886670T
Approximate Age: 31 years
Height: 70 inches
Weight: 189.8 lbs.
Sex: Male
We hereby certify that on this day, October 20, 2012, pursuant to Statute 49.25 of City Code, an autopsy on the body of Daniel William Egleston was performed at the Fulton County Medical Examiner's Office in Atlanta. And in accordance with Resurrection Prevention Laws, we hereby certify that the subject in question will be terminated permanently, using appropriate brain-destructive techniques, which have been certified by the Fulton County Health Commissioner's Office.
Upon investigation of the essential facts concerning the circumstances of the death and history of the case, we are of the opinion that the cause of death was as follows:
Upon investigation of the essential facts concerning the circumstances of the death and history of the case, we are of the opinion that the cause of death was as follows:
FINDINGS:
I. Sudden death associated with:
1. Exsanguination – Bleeding to death from gunshot wound to the sternum and intestines
2. Hypoxia by pneumothorax – Deprived of adequate oxygen
II. Perforating injury
III. Hepatomegaly (weight = 1695 gms) with mild fatty metamorphosis
IV. Prostatic hyperplasia, mild
V. Postmortem toxicology:
1. Cardiac blood fluoxetine = 2.72 ug/mL
2. Femoral vein blood fluoxetine = 0.778 ug/mL
VI. Postmortem blood 20 heavy metal screen negative
COMMENT:
Daniel William Egleston was 31 years of age at the time of his death. He was a sales clerk, shot in Centennial Olympic Park, where he was apparently discovered unresponsive, along with his wife. The exact downtime is unknown but could be as much as 20 minutes or more before he was discovered unresponsive. The ambulance arrived at 11:08 p.m. and he was transported to Emory Hospital, where immediate life support protocols were instituted. However, he was pronounced [sic] dead at 12:01 p.m.
CAUSE OF DEATH: DEATH DUE TO BALLISTIC TRAUMA (FOUL PLAY)
MANNER OF DEATH: UNNATURAL
---*
I. CLOTHING AND PERSONAL EFFECTS: The body is presented to the morgue secured in a body bag and clad in:
1. White button-up shirt
2. Black pants (cut)
3. Pair of white socks
EXTERNAL BODY DESCRIPTION:
Except for the gunshot wounds, the body WAS that of a normally developed, well-nourished and well-hydrated, adult Caucasian male appearing somewhat older than the given age of 31 years, with a body length of 70 inches and body weight of 189.9 pounds. The body was well-preserved, unembalmed and cool post refrigeration. Rigor was not fully developed. Lividity was developed, posterior, dependent, purple and slightly blanchable.
The scalp was covered by short, straight brown and occasional gray hair with slight frontal, sagittal and occipital pattern baldness. The face was shaven. Body hair was male distribution and average.
Subject began showing signs of Z-1 and Z-2 infection at 12:53 p.m., approximately 52 minutes after death was declared. The body began to show a fever, despite having been dead and cold to the touch for almost an hour. Temperature was taken, showing 109.4 F (43 C), until finally it began to "cool" to around 101.2 F.
Subject's body began twitching at 1:04 p.m., not terribly uncommon in the recently deceased. However, the eyelids opened at 1:27 p.m. and moved about, showing definite signs of awareness. Subject moved his lips, pushed air out from his mouth four times, and reached for Dr. Brewer, feeling of his labcoat, as though he was familiar with the texture. At 1:35 p.m., after generally reaching about at other objects around the table he was laid on, subject suddenly went into convulsions and closed his eyes again. Subject inert at 1:37 p.m.
2:02 p.m.: Z-1 infection has completely morphed into Z-2. Subject's body temperature suddenly plummeted. Within the span of a few minutes, the temperature dropped from 98.6 F (37 C) to around 71.6 F (22 C). Though liver, heart and lungs have all ceased functioning, the eyes have once again opened, and the arms are reaching out, this time not just to Dr. Brewer, but to others in the room, as well.
2:09 p.m.: subject has gone inert again. I enacted Z-ready protocols and advised medical team to maintain a three-foot distance from subject, as Z-2 sufferers are known to be erratic.
At 2:17 p.m., subject suddenly became very animated, and reached out to grab hold of Dr. Sanderson (despite my instructions, Dr. Sanderson chose to examine the subject's eyes). Sanderson was bit; a large section of flesh was removed from her right wrist and forearm. Subject on the table appeared angry and violent. Dr. Sanderson was removed from the room.
At 2:32 p.m., I contacted the other chief medical examiner, Dr. Peter Fong, and asked him how we ought to proceed. Dr. Fong advised close adherence to Statute 50.21 of City Code, and asked me to contact subject's family.
3:15 p.m.: The Egleston family arrived. Two younger brothers (Darryl and Ernest) and the older sister (Pamela) to the subject. At this point, as per my instructions, the body had been restrained by four male nurses, and strapped to the table. Upon seeing their brother lying there, writhing, angry, and snapping at them whenever they tried to go near, the Egleston family signed the papers and determined that the subject's time of death was indeed 12:01 p.m.
At 3:38 p.m., under the watch of the subject's surviving family and Chief Medical Examiner Dr. Peter Fong, myself and Dr. Brewer performed the final immobilization: we used the captive bolt pistol, in accordance with state law for Z-2 sufferers, and placed the nozzle on the right temple of the subject's head. The firing pin penetrated the skull and destroyed the brain. We performed this procedure twice more, from the left temple and from the base of the skull, to make sure that the subject was not able to move again.
At 3:52 p.m., in accordance with the No-Reanimation Law recently enacted by the POTUS, and the rules and guidelines set down in the U.N. Z-2 Emergency Summit, subject's body was moved to the incinerator without any further public viewing.
Blood and toxicology tests performed on minor necrotic cells and blood samples gathered before Z-2 onset.
FINAL NOTE: At 4:03 a.m., Dr. Sanderson began showing signs of Z-1.
Subject began showing signs of Z-1 and Z-2 infection at 12:53 p.m., approximately 52 minutes after death was declared. The body began to show a fever, despite having been dead and cold to the touch for almost an hour. Temperature was taken, showing 109.4 F (43 C), until finally it began to "cool" to around 101.2 F.
Subject's body began twitching at 1:04 p.m., not terribly uncommon in the recently deceased. However, the eyelids opened at 1:27 p.m. and moved about, showing definite signs of awareness. Subject moved his lips, pushed air out from his mouth four times, and reached for Dr. Brewer, feeling of his labcoat, as though he was familiar with the texture. At 1:35 p.m., after generally reaching about at other objects around the table he was laid on, subject suddenly went into convulsions and closed his eyes again. Subject inert at 1:37 p.m.
2:02 p.m.: Z-1 infection has completely morphed into Z-2. Subject's body temperature suddenly plummeted. Within the span of a few minutes, the temperature dropped from 98.6 F (37 C) to around 71.6 F (22 C). Though liver, heart and lungs have all ceased functioning, the eyes have once again opened, and the arms are reaching out, this time not just to Dr. Brewer, but to others in the room, as well.
2:09 p.m.: subject has gone inert again. I enacted Z-ready protocols and advised medical team to maintain a three-foot distance from subject, as Z-2 sufferers are known to be erratic.
At 2:17 p.m., subject suddenly became very animated, and reached out to grab hold of Dr. Sanderson (despite my instructions, Dr. Sanderson chose to examine the subject's eyes). Sanderson was bit; a large section of flesh was removed from her right wrist and forearm. Subject on the table appeared angry and violent. Dr. Sanderson was removed from the room.
At 2:32 p.m., I contacted the other chief medical examiner, Dr. Peter Fong, and asked him how we ought to proceed. Dr. Fong advised close adherence to Statute 50.21 of City Code, and asked me to contact subject's family.
3:15 p.m.: The Egleston family arrived. Two younger brothers (Darryl and Ernest) and the older sister (Pamela) to the subject. At this point, as per my instructions, the body had been restrained by four male nurses, and strapped to the table. Upon seeing their brother lying there, writhing, angry, and snapping at them whenever they tried to go near, the Egleston family signed the papers and determined that the subject's time of death was indeed 12:01 p.m.
At 3:38 p.m., under the watch of the subject's surviving family and Chief Medical Examiner Dr. Peter Fong, myself and Dr. Brewer performed the final immobilization: we used the captive bolt pistol, in accordance with state law for Z-2 sufferers, and placed the nozzle on the right temple of the subject's head. The firing pin penetrated the skull and destroyed the brain. We performed this procedure twice more, from the left temple and from the base of the skull, to make sure that the subject was not able to move again.
At 3:52 p.m., in accordance with the No-Reanimation Law recently enacted by the POTUS, and the rules and guidelines set down in the U.N. Z-2 Emergency Summit, subject's body was moved to the incinerator without any further public viewing.
Blood and toxicology tests performed on minor necrotic cells and blood samples gathered before Z-2 onset.
FINAL NOTE: At 4:03 a.m., Dr. Sanderson began showing signs of Z-1.
TOXICOLOGY TEST RESULTS
OFFICE OF CHIEF MEDICAL EXAMINER SUSAN LUDNER, M.D., DABFP
TOXICOLOGY LABORATORY SERVICE CHIEF MEDICAL EXAMINER
ATLANTA CENTRAL TERRY BREWER, PH.D., DABFT
FULTON COUNTY, ATLANTA CITY CHIEF TOXICOLOGIST
NAME: DANIEL WILLIAM EGLESTON PRIORITY: 1
M.E. CASE NUMBER: 886670T M.E. TOX NUMBER: 7780333T-XX
BLOOD ETHANOL NEG
URINE ETHANOL NEG
URINE COCAINE NEG
URINE CANNABINOIDS NEG
URINE OPIATES NEG
BLOOD ABN (HEART) POS FLUOXETINE 2.630 UG/ML
BLOOD ABN (HEART) POS NORFLUOXETINE 1.850 UG/ML
BLOOD ABN (HEART) POS NORFLUOXETINE 1.850 UG/ML
URINE ABN POS NORFLUOXETINE 2.260 UG/ML
GASTRIC ABN POS NORFLUOXETINE 1.077 UG/ML
LIVER NORFLUOXETINE POS NORFLUOXETINE 48.810 UG/ML
For INJURIES, INTERNAL EXAMINATION, SPECIMENS, and MICROSCOPIC DESCRIPTIONS, see page(s) 4-10.
[Dr. Samuel P. Brice]
Follow me on Twitter and Facebook: Twitter account name ChadHuskinsAuthor
Follow me on Twitter and Facebook: Twitter account name ChadHuskinsAuthor
Wednesday, April 16, 2014
I Got a Part in a Zombie Flick...and All My Novels Are FREE as Ebooks This Weekend!
Hey guys, all my novels are going to be free in their ebook forms this weekend:
http://www.amazon.com/Psycho-Save-The-Series-Book-ebook/dp/B009DL5WEQ
Also, the podcast is doing great. If you get a chance, check it out: http://www.ideasarespecial.libsyn.com/
And yeah, about that zombie flick. It's called Test Group, and you can check out the production and all the updates on their Facebook page, Atlanta Zombie Film!
http://www.amazon.com/Psycho-Save-The-Series-Book-ebook/dp/B009DL5WEQ
Also, the podcast is doing great. If you get a chance, check it out: http://www.ideasarespecial.libsyn.com/
And yeah, about that zombie flick. It's called Test Group, and you can check out the production and all the updates on their Facebook page, Atlanta Zombie Film!
Thursday, March 6, 2014
Podcast Up and Running! MonsterCon is a go!
Our podcast is up, and it's called "Ideas Are Special" because...ya know...they are! Check it out here.
My co-host is my long-time friend and troublemaker Dylan Harwood. We discuss everything from pop culture to TV to writing to Bronies...and we submit ourselves to the horror that is the Brony Challenge, all for your amusement. Give it a listen, subscribe, tell us if you love it, hate it, have fun with it, let us know what features you'd like to see or hear in the future.
Also, the script for the Psycho Save Us film is being worked up by filmmaker John Harkrider, who purchased the film rights two months ago.
And lastly, myself and my editor are going to be at a few cons this year. We know for certain we're going to have a panel/booth at MonsterCon, which is the relatively new big sci-fi/comic convention in South Carolina. It looks like we'll be at DragonCon as well. I'll also be attending ComicCon in San Diego. Hope to see you guys there!
Got a lotta irons in the fire.
Check out Psycho Save Us at Amazon for a good, frightening read!
My co-host is my long-time friend and troublemaker Dylan Harwood. We discuss everything from pop culture to TV to writing to Bronies...and we submit ourselves to the horror that is the Brony Challenge, all for your amusement. Give it a listen, subscribe, tell us if you love it, hate it, have fun with it, let us know what features you'd like to see or hear in the future.
Also, the script for the Psycho Save Us film is being worked up by filmmaker John Harkrider, who purchased the film rights two months ago.
And lastly, myself and my editor are going to be at a few cons this year. We know for certain we're going to have a panel/booth at MonsterCon, which is the relatively new big sci-fi/comic convention in South Carolina. It looks like we'll be at DragonCon as well. I'll also be attending ComicCon in San Diego. Hope to see you guys there!
Got a lotta irons in the fire.
Check out Psycho Save Us at Amazon for a good, frightening read!
Wednesday, February 5, 2014
Film Rights to "Psycho Save Us"...SOLD!
Exciting news, guys! Filmmaker John Harkrider has purchased the film rights to Psycho Save Us, and is now moving forward with scripting and production. Harkrider has won praise at Sundance Film Festivals, and is known for his breakout debut with the film Mitchellville. Variety listened him in their Top Ten List of directors to watch.
If you haven't read Psycho Save Us yet, or its sequel, Psycho Within Us...now's the time to get acquainted with Spencer, Kaley, and Shannon.
http://www.amazon.com/Psycho-Save-The-Series-Book-ebook/dp/B009DL5WEQ
If you haven't read Psycho Save Us yet, or its sequel, Psycho Within Us...now's the time to get acquainted with Spencer, Kaley, and Shannon.
http://www.amazon.com/Psycho-Save-The-Series-Book-ebook/dp/B009DL5WEQ
Saturday, October 20, 2012
Zombie Autopsy: How Do Zombies Work, Exactly?
Zombies. Just say the word and get people's attention. For whatever reason, there has been a resurrection (pardon the pun) of interest in zombies over the last decade. Though filmmaker George A. Romero is usually credited with creating our contemporary understanding of zombies with the 1968 classic Night of the Living Dead, tales of zombies have been around since about 1918, and of course stories of general resurrection predate even that, but those are religious tales, the more supernatural kind.
We won't be talking about these zombies. We'll be talking about Romero-style zombies, and/or The Walking Dead-type zombies because, well, I have a lot of questions when it comes to exactly how someone could be technically dead, yet still walk, exhibit enough strength to sometimes rip and tear flesh like a grizzly bear, yet continue to show obvious signs of decay. How could they (conceivably) work?
I'm a writer, and as a writer I have an interest in research. The tricky part for a writer is doing all the research and then burying it, so that it doesn't interfere with your narrative, so that you have a story and not a how-to manual. But, in the interest of exploring this concept, doing our research (even if it's just exploratory and maybe for posterity's sake), and because it's almost Halloween, here we go.
I present to you...drumroll please...
Zombie Autopsy!
The Resurrection Process
All right, so, we'll start from the start. How can a person return from the dead, move about like they're alive, see with their eyes and hear with their ears, yet still have necrosis (decay) taking place in almost all important skin, muscle, and other tissue cells?
As it happens, this has been explored in actual, real-world research before, because, believe it or not, there were supposed zombies in real life in Haiti, at least as far back as 1980, when a man walked into a village and claimed to be Clairvius Narcisse, a man that had died in a hospital in Deschapelles, May 2, 1962. He had memories of Narcisse's life that even close relatives had forgotten. Other Haitian zombies have materialized through the years.
Dr. Wade Davis, an anthropologist and ethnobotanist, conducted extensive research and came to the conclusion that the "Haitian zombie" phenomenon was caused by a rare drug, called tetrododoxin, which comes from the puffer fish. Combined with toxins from a native tree toad and other chemicals, it could be made into a powder that could put people so close to death that it was difficult to determine whether or not they were alive. They could also be brought back, and while most suffered long-lasting effects, some fully recovered! But a few returned and, while cognizant, had lost some fine motor skills. This powder could kill someone, yet keep them in a rare state where resurrection was still possible, and place the living in a condition where they lost many motor skills and had only faint life signs (like a zombie).
But zombism is obviously brought on by a pathogen, not a powder. So, from here one, we shall refer to this pathogon as "Z-1" for simplicity's sake.
Virology
Bites from zombies, such as those in The Walking Dead, show that zombism is communicable and therefore lend more credence that this is a pathogen. It causes tremors and terrible fever. Z-1 probably behaves much like malaria, first hiding within the liver, where it multiplies and grows stronger. Then, once it has marshaled enough forces, it invades the bloodstream, where it infects red blood cells. Now come the symptoms: fever, shivering, anemia, vomiting, and convulsions.
After that, Z-1 obviously shuts down the higher brain functions but leaves the most basic sensory perceptions. But Z-1 shows how diverse it is by not only affecting brain and motor functions, but also damaging other major tissues separate from the brain.
To attack humans so specifically, and not other animals like dogs and cats, Z-1 is probably either a single- or double-stranded DNA virus. This means it actually has DNA as its genetic material and replicates using DNA-dependent DNA polymerase: an enzyme that acts as a catalyst. Z-1 therefore probably shares a morphology not unlike Herpesvirales (the herpes virus). And, like herpes, you can catch it from a bite.
While a bite accelerates the infection we are all carrying the Z-1 virus, just as 1/3 of us are carrying tuberculosis around without any ill effects (for the most part). This is why those dead from natural causes or accidents also succumb to Z-1, which indicates that Z-1 is lying in wait for the immune system to "switch off" so it can have its day in the sun.
Necrotic Skin and Bone
Flesh sloughing off, turning blue and gray, and generally remaining damaged long after wounds ought to have scabbed over; all of these indicate that Z-1 has a unique effect on human skin.
Oxygen blockages to skin cells causes necrosis; that's the premature death of cells in living tissue. Necrosis can happen to the living in various ways, including snake and spider bites, which indicates that Z-1 lives very, very well in human saliva, and, like the bite from a brown recluse spider, it begins a slow process of killing tissues. But that doesn't mean it has to kill muscle tissues--only skin and flesh tend to decay, at least initially. When zombies are injured by stupidly running into things or getting shot, the wound never heals because skin cells are dead, and the immune system, rocked by the other effects of Z-1, cannot address the problems of infections by other organisms, which only increases decay.
Given enough time, Z-1 causes necrosis of bone cells, which brings on symptoms similar to osteogenesis imperfecta (brittle bone disease), of a Type IV kind or above. In this phase of zombism, bones are easily fractured. This is why "older" zombies (those who've had Z-1 the longest and have gone through all the major cellular breakdown stages) are mushier, easier to hack into pieces, almost exactly like a corpse.
The Brain
Like many viruses, Z-1 must mutate in order to survive. Otherwise, it would be easy to catch and kill. Therefore, after Z-1 has grown strong in the liver and successfully invaded the bloodstream, it quickly mutates into a whole new strand, known as Z-2, and migrates into the brain to live out the rest of its days.
The fact that zombies can still see means that Z-2 does not have much of an effect on the occipital lobe; the visual cortex. Gray matter in the brain is obviously influenced in a very special way (gray matter controls sensory perception, muscle control, emotions, speech, hearing and memory). A condition known as "gray matter heterotopia" can cause seizures, loss of higher brain functions, and mental retardation. Z-2 imitates these symptoms by "slushing" the brain, causing severe swelling and thus moving portions of gray matter around, exactly as heterotopia does.
Z-2 shuts down most of the brain's other regions. The frontal lobe, which controls the ability to recognize future consequences of current actions, is almost completely shut down. In most sufferers, Z-2 shuts down the parietal lobe, too, which means they cannot manipulate objects at all. However, some zombies do show the ability to figure out simple objects, such as doorknobs, which indicates Z-2 doesn't always attack the parietal lobe so aggressively.
As far as motor functions go, Z-2 initially behaves much like Guillain-Barre Syndrome (GBS). GBS is an acute neuropathy, which is a disorder that affects the peripheral nervous system. In short, you lose control of your limbs. Even after a body recovers from GBS, coordination is extremely difficult, survivors can't run as fast as they did before (at least, not without rehabilitation). This would explain why zombies usually can't run as fast as they did when they were alive, yet can still stand and move about. They've "survived" the first initial shock of Z-2 on their brain, but the communication between brain and muscles has been damaged forever, causing a lack of coordination.
Zombie Strength
Zombies often show that they can pry a person's belly open just with their bare hands. How is this possible?
Well, under extreme circumstances, normal human beings have been known to exhibit incredible strength not thought possible. This phenomenon is called "hysterical strength." (Is there anything more hysterical than a zombie?) Hysterical strength most commonly occurs when someone is single-minded, not caring about the consequences. It happens in torn muscles and damaged joints: of course, sufferers of Z-2 have lots of damages to their bodies.
The brain (which we covered above) controls everything in the human body, including limiting the number of muscle fibers the body can use at once: this prevents you from overexerting and hurting yourself. The brain also motivates the processes that create lactic acids, which also factor in. Since Z-2 shuts down so much of the brain, it not only leaves the zombie without lactic acid production, it also allows a zombie to use its maximum strength (practically every muscle fiber in its entire body) to rip and tear and rend. Jaw muscles are affected, just like everything else, so this gives the zombie the ability to bite so hard it can tear off huge chunks of human flesh in one bite.
This is why, while zombies appear flimsy, clumsy, and sometimes mushy, they can demonstrate incredible power when they've got their hands on a victim.
Insatiable Hunger
Back to the brain for this one. Z-2 obviously affects the hypothalamus region of the brain in a very unique way. There are two parts of the hypothalamus that control eating and hunger. The lateral hypothalamus gives the signal when it's time to start eating, and the ventromedial nucleus gives the signal when it's time to stop eating. Human beings only feel satiated when the ventromedial nucleus is functioning properly. Z-2 sufferers often have this part of their brain operating at such a low level that it's practically dead.
Real-world evidence shows that people who have had their ventromedial nucleus injured are unable to determine when they should stop eating.
Incidentally, this region also helps control fear and sexual activity: the fact that this region of the brain is nearly dead shows just how much humanity Z-2 robs of its victims.
Inhuman Growling
"New" zombies typically only moan or hiss. But over time, necrotic damage to the esophagus and vocal cords cause many zombies to begin pushing wind through nothing more than a leaking pipe. Their throat and lungs begin to fill with liquid, and they are now gurgling more than growling. This creates an unpleasant gurgle/growl in "older" zombies.
However, if their lungs are filled with liquid, we get some interesting questions. How do zombies continue to move when the brain depends on oxygen and blood delivered to it from other parts of the body? How can Z-2 survive in the brain at all, since the brain must surely and eventually die due to asphyxiation and ischemia? That is, without the lungs functioning, or the heart, how does the brain receive air and blood?
The answer: It doesn't.
Z-2 sufferers still take in ample amounts of flesh (human flesh is their favorite), and this provides incredible energy for the brain to continue to function, replacing the need for oxygen and steady bloodflow altogether. Z-2 is therefore not just a virus, but a powerful new agent that transforms the body's normal processes and ultimately serves as a very specialized life-support system for the brain, and the brain alone.
Because of this, Z-2 is able to sustain itself a very, very long time, as long as it remains in its comfortable "cradle" inside the base of the brain. As long as nerves and connective tissues remain intact, Z-1 can keep the brain going enough to send the basest commands to its limbs.
It is not yet known how long it would take for Z-1 to die on its own.
Origin and Final Analysis
It's possible that Z-1 was manmade, as many have hypothesized. One clue is that, as stated above, it targets the human hypothalamus, making it yearn for sustenance, but does not affect the brains of other animals. And while zombies will feast on other animals if they have to, they obviously prefer a fresh human meal, yet do not often feed on each other. They care not for their fellow dead, they show no sign of loss when one of their own gets shot or decapitated, and they lust only for flesh from the living.
Perhaps Z-1 only makes its victims "dance," makes of them puppets. If not...
If not, then it indicates that when everything else is stripped away, when all pretenses of society and community are removed, and when human beings are laid bare and left with only their basest desires, they have only one craving, one thing that they want more than anything else: the destruction of one another. Not to hug or make love, not to make picnics or hold hands. But to devour that which they hate most. Themselves.
A pathogen that causes humans to target humans. Certainly sounds manmade. Or else, the wrath of Nature.
For a more detailed autopsy, please see below:
Autopsy of Z-1 Sufferer
-------------------------------
Office of the Chief Medical Examiner
Fulton County 2nd District
Atlanta, GA
AUTOPSY REPORT
Male Subject - Daniel William Egleston
Case No. 886670T
Approximate Age: 31 years
Height: 70 inches
Weight: 189.8 lbs.
Sex: Male
We won't be talking about these zombies. We'll be talking about Romero-style zombies, and/or The Walking Dead-type zombies because, well, I have a lot of questions when it comes to exactly how someone could be technically dead, yet still walk, exhibit enough strength to sometimes rip and tear flesh like a grizzly bear, yet continue to show obvious signs of decay. How could they (conceivably) work?
I'm a writer, and as a writer I have an interest in research. The tricky part for a writer is doing all the research and then burying it, so that it doesn't interfere with your narrative, so that you have a story and not a how-to manual. But, in the interest of exploring this concept, doing our research (even if it's just exploratory and maybe for posterity's sake), and because it's almost Halloween, here we go.
I present to you...drumroll please...
Zombie Autopsy!
The Resurrection Process
All right, so, we'll start from the start. How can a person return from the dead, move about like they're alive, see with their eyes and hear with their ears, yet still have necrosis (decay) taking place in almost all important skin, muscle, and other tissue cells?
As it happens, this has been explored in actual, real-world research before, because, believe it or not, there were supposed zombies in real life in Haiti, at least as far back as 1980, when a man walked into a village and claimed to be Clairvius Narcisse, a man that had died in a hospital in Deschapelles, May 2, 1962. He had memories of Narcisse's life that even close relatives had forgotten. Other Haitian zombies have materialized through the years.
Dr. Wade Davis, an anthropologist and ethnobotanist, conducted extensive research and came to the conclusion that the "Haitian zombie" phenomenon was caused by a rare drug, called tetrododoxin, which comes from the puffer fish. Combined with toxins from a native tree toad and other chemicals, it could be made into a powder that could put people so close to death that it was difficult to determine whether or not they were alive. They could also be brought back, and while most suffered long-lasting effects, some fully recovered! But a few returned and, while cognizant, had lost some fine motor skills. This powder could kill someone, yet keep them in a rare state where resurrection was still possible, and place the living in a condition where they lost many motor skills and had only faint life signs (like a zombie).
But zombism is obviously brought on by a pathogen, not a powder. So, from here one, we shall refer to this pathogon as "Z-1" for simplicity's sake.
Virology
Bites from zombies, such as those in The Walking Dead, show that zombism is communicable and therefore lend more credence that this is a pathogen. It causes tremors and terrible fever. Z-1 probably behaves much like malaria, first hiding within the liver, where it multiplies and grows stronger. Then, once it has marshaled enough forces, it invades the bloodstream, where it infects red blood cells. Now come the symptoms: fever, shivering, anemia, vomiting, and convulsions.
After that, Z-1 obviously shuts down the higher brain functions but leaves the most basic sensory perceptions. But Z-1 shows how diverse it is by not only affecting brain and motor functions, but also damaging other major tissues separate from the brain.
To attack humans so specifically, and not other animals like dogs and cats, Z-1 is probably either a single- or double-stranded DNA virus. This means it actually has DNA as its genetic material and replicates using DNA-dependent DNA polymerase: an enzyme that acts as a catalyst. Z-1 therefore probably shares a morphology not unlike Herpesvirales (the herpes virus). And, like herpes, you can catch it from a bite.
While a bite accelerates the infection we are all carrying the Z-1 virus, just as 1/3 of us are carrying tuberculosis around without any ill effects (for the most part). This is why those dead from natural causes or accidents also succumb to Z-1, which indicates that Z-1 is lying in wait for the immune system to "switch off" so it can have its day in the sun.
Necrotic Skin and Bone
Flesh sloughing off, turning blue and gray, and generally remaining damaged long after wounds ought to have scabbed over; all of these indicate that Z-1 has a unique effect on human skin.
Oxygen blockages to skin cells causes necrosis; that's the premature death of cells in living tissue. Necrosis can happen to the living in various ways, including snake and spider bites, which indicates that Z-1 lives very, very well in human saliva, and, like the bite from a brown recluse spider, it begins a slow process of killing tissues. But that doesn't mean it has to kill muscle tissues--only skin and flesh tend to decay, at least initially. When zombies are injured by stupidly running into things or getting shot, the wound never heals because skin cells are dead, and the immune system, rocked by the other effects of Z-1, cannot address the problems of infections by other organisms, which only increases decay.
Given enough time, Z-1 causes necrosis of bone cells, which brings on symptoms similar to osteogenesis imperfecta (brittle bone disease), of a Type IV kind or above. In this phase of zombism, bones are easily fractured. This is why "older" zombies (those who've had Z-1 the longest and have gone through all the major cellular breakdown stages) are mushier, easier to hack into pieces, almost exactly like a corpse.
The Brain
Like many viruses, Z-1 must mutate in order to survive. Otherwise, it would be easy to catch and kill. Therefore, after Z-1 has grown strong in the liver and successfully invaded the bloodstream, it quickly mutates into a whole new strand, known as Z-2, and migrates into the brain to live out the rest of its days.
The fact that zombies can still see means that Z-2 does not have much of an effect on the occipital lobe; the visual cortex. Gray matter in the brain is obviously influenced in a very special way (gray matter controls sensory perception, muscle control, emotions, speech, hearing and memory). A condition known as "gray matter heterotopia" can cause seizures, loss of higher brain functions, and mental retardation. Z-2 imitates these symptoms by "slushing" the brain, causing severe swelling and thus moving portions of gray matter around, exactly as heterotopia does.
Z-2 shuts down most of the brain's other regions. The frontal lobe, which controls the ability to recognize future consequences of current actions, is almost completely shut down. In most sufferers, Z-2 shuts down the parietal lobe, too, which means they cannot manipulate objects at all. However, some zombies do show the ability to figure out simple objects, such as doorknobs, which indicates Z-2 doesn't always attack the parietal lobe so aggressively.
As far as motor functions go, Z-2 initially behaves much like Guillain-Barre Syndrome (GBS). GBS is an acute neuropathy, which is a disorder that affects the peripheral nervous system. In short, you lose control of your limbs. Even after a body recovers from GBS, coordination is extremely difficult, survivors can't run as fast as they did before (at least, not without rehabilitation). This would explain why zombies usually can't run as fast as they did when they were alive, yet can still stand and move about. They've "survived" the first initial shock of Z-2 on their brain, but the communication between brain and muscles has been damaged forever, causing a lack of coordination.
Zombie Strength
Zombies often show that they can pry a person's belly open just with their bare hands. How is this possible?
Well, under extreme circumstances, normal human beings have been known to exhibit incredible strength not thought possible. This phenomenon is called "hysterical strength." (Is there anything more hysterical than a zombie?) Hysterical strength most commonly occurs when someone is single-minded, not caring about the consequences. It happens in torn muscles and damaged joints: of course, sufferers of Z-2 have lots of damages to their bodies.
The brain (which we covered above) controls everything in the human body, including limiting the number of muscle fibers the body can use at once: this prevents you from overexerting and hurting yourself. The brain also motivates the processes that create lactic acids, which also factor in. Since Z-2 shuts down so much of the brain, it not only leaves the zombie without lactic acid production, it also allows a zombie to use its maximum strength (practically every muscle fiber in its entire body) to rip and tear and rend. Jaw muscles are affected, just like everything else, so this gives the zombie the ability to bite so hard it can tear off huge chunks of human flesh in one bite.
This is why, while zombies appear flimsy, clumsy, and sometimes mushy, they can demonstrate incredible power when they've got their hands on a victim.
Insatiable Hunger
Back to the brain for this one. Z-2 obviously affects the hypothalamus region of the brain in a very unique way. There are two parts of the hypothalamus that control eating and hunger. The lateral hypothalamus gives the signal when it's time to start eating, and the ventromedial nucleus gives the signal when it's time to stop eating. Human beings only feel satiated when the ventromedial nucleus is functioning properly. Z-2 sufferers often have this part of their brain operating at such a low level that it's practically dead.
Real-world evidence shows that people who have had their ventromedial nucleus injured are unable to determine when they should stop eating.
Incidentally, this region also helps control fear and sexual activity: the fact that this region of the brain is nearly dead shows just how much humanity Z-2 robs of its victims.
Inhuman Growling
"New" zombies typically only moan or hiss. But over time, necrotic damage to the esophagus and vocal cords cause many zombies to begin pushing wind through nothing more than a leaking pipe. Their throat and lungs begin to fill with liquid, and they are now gurgling more than growling. This creates an unpleasant gurgle/growl in "older" zombies.
However, if their lungs are filled with liquid, we get some interesting questions. How do zombies continue to move when the brain depends on oxygen and blood delivered to it from other parts of the body? How can Z-2 survive in the brain at all, since the brain must surely and eventually die due to asphyxiation and ischemia? That is, without the lungs functioning, or the heart, how does the brain receive air and blood?
The answer: It doesn't.
Z-2 sufferers still take in ample amounts of flesh (human flesh is their favorite), and this provides incredible energy for the brain to continue to function, replacing the need for oxygen and steady bloodflow altogether. Z-2 is therefore not just a virus, but a powerful new agent that transforms the body's normal processes and ultimately serves as a very specialized life-support system for the brain, and the brain alone.
Because of this, Z-2 is able to sustain itself a very, very long time, as long as it remains in its comfortable "cradle" inside the base of the brain. As long as nerves and connective tissues remain intact, Z-1 can keep the brain going enough to send the basest commands to its limbs.
It is not yet known how long it would take for Z-1 to die on its own.
Origin and Final Analysis
It's possible that Z-1 was manmade, as many have hypothesized. One clue is that, as stated above, it targets the human hypothalamus, making it yearn for sustenance, but does not affect the brains of other animals. And while zombies will feast on other animals if they have to, they obviously prefer a fresh human meal, yet do not often feed on each other. They care not for their fellow dead, they show no sign of loss when one of their own gets shot or decapitated, and they lust only for flesh from the living.
Perhaps Z-1 only makes its victims "dance," makes of them puppets. If not...
If not, then it indicates that when everything else is stripped away, when all pretenses of society and community are removed, and when human beings are laid bare and left with only their basest desires, they have only one craving, one thing that they want more than anything else: the destruction of one another. Not to hug or make love, not to make picnics or hold hands. But to devour that which they hate most. Themselves.
A pathogen that causes humans to target humans. Certainly sounds manmade. Or else, the wrath of Nature.
For a more detailed autopsy, please see below:
Autopsy of Z-1 Sufferer
-------------------------------
Office of the Chief Medical Examiner
Fulton County 2nd District
Atlanta, GA
AUTOPSY REPORT
Male Subject - Daniel William Egleston
Case No. 886670T
Approximate Age: 31 years
Height: 70 inches
Weight: 189.8 lbs.
Sex: Male
We
hereby certify that on this day, October 20, 2012, pursuant to Statute 49.25 of City Code, an
autopsy on the body of Daniel William Egleston was performed at the Fulton County Medical
Examiner's Office in Atlanta, and upon investigation of the essential facts
concerning the circumstances of the death and history of the case, we are of
the opinion that the cause of death was as follows:
FINDINGS:
I.
Sudden death associated with:
1. Exsanguination – Bleeding to death from gunshot wound to the sternum and intestines
2. Hypoxia by pneumothorax – Deprived of adequate oxygen
3. Heart failure (HF)
4. Traumatic brain damage (TBI) –
degeneration of brain cells
II.
Perforating injury
Ill.
Hepatomegaly (weight = 1695 gms) with mild fatty metamorphosis
IV.
Prostatic hyperplasia, mild
VI.
No evidence of dehydration or electrolyte imbalance:
1. Postmortem vitreous chemistry non-contributory
2. Blood furosemide (Lasix) negative
VII.
Postmortem toxicology:
1. Cardiac blood fluoxetine = 2.72 ug/mL
2. Femoral vein blood fluoxetine = 0.778 ug/mL
3. Gastric fluoxetine = 4.2 ug/mL
4. Liver fluoxetine = 61.4 ug/mL
VIII.
Postmortem blood 20 heavy metal screen negative
IX.
Postmortem blood mercury negative (below detection level)
COMMENT:
Daniel William Egleston was 31 years of age at the time of his death. He was a sales clerk, shot in Centennial Olympic Park, where he was apparently discovered unresponsive, along
with his wife. The exact downtime is
unknown but could be as much as 20 minutes or more before he was discovered
unresponsive. The ambulance arrived at
11:08 p.m. and he was transported to Columbia Metropolitan Hospital, where
immediate life support protocols were instituted. However, he was pronounced [sic] dead at
12:01 p.m.
CAUSE
OF DEATH:
DEATH DUE TO BALLISTIC TRAUMA (FOUL PLAY)
MANNER
OF DEATH: UNNATURAL
Signature
Chenzira A. Tefni, M.D.
Signature
Susan Ludner, M.D.
A
CERTIFIED COPY ATTEST SUSAN LUDNER, M.D. CHIEF MEDICAL EXAMINER COBB COUNTY,
[signature] Wanda Peterson
GROSS
ANATOMICAL DESCRIPTION
---*
I.
CLOTHING AND PERSONAL EFFECTS: The body is presented to the morgue secured in a
body bag and clad in:
1.
White button-up shirt
2.
Black pants (cut)
3.
Pair of white socks
EXTERNAL
BODY DESCRIPTION:
Except
for the gunshot wounds, the body WAS that of a normally developed,
well-nourished and well-hydrated, adult Caucasian male appearing somewhat older
than the given age of 31 years, with a body length of 70 inches and body weight
of 189.9 pounds. The body was well-preserved, unembalmed and
cool post refrigeration. Rigor was not fully
developed. Lividity was developed,
posterior, dependent, purple and slightly blanchable.
The
scalp was covered by short, straight brown and occasional gray hair with slight frontal,
sagittal and occipital pattern baldness. The face was shaven. Body hair was male distribution and average.
Subject began showing signs of Z-1 and Z-2 infection at 12:53 p.m., approximately 52 minutes after death was declared. The body began to show a fever, despite having been dead and cold to the touch for almost an hour. Temperature was taken, showing 109.4 F (43 C), until finally it began to "cool" to around 101.2 F.
Subject's body began twitching at 1:04 p.m., not terribly uncommon in the recently deceased. However, the eyelids opened at 1:27 p.m. and moved about, showing definite signs of awareness. Subject moved his lips, pushed air out from his mouth four times, and reached for Dr. Brewer, feeling of his labcoat, as though he was familiar with the texture. At 1:35 p.m., after generally reaching about at other objects around the table he was laid on, subject suddenly went into convulsions and closed his eyes again. Subject inert at 1:37 p.m.
2:02 p.m.: Z-1 infection has completely morphed into Z-2. Subject's body temperature suddenly plummeted. Within the span of a few minutes, the temperature dropped from 98.6 F (37 C) to around 71.6 F (22 C). Though liver, heart and lungs have all ceased functioning, the eyes have once again opened, and the arms are reaching out, this time not just to Dr. Brewer, but to others in the room, as well.
2:09 p.m.: subject has gone inert again. I enacted Z-ready protocols and advised medical team to maintain a three-foot distance from subject, as Z-2 sufferers are known to be erratic.
At 2:17 p.m., subject suddenly became very animated, and reached out to grab hold of Dr. Sanderson (despite my instructions, Dr. Sanderson chose to examine the subject's eyes). Sanderson was bit; a large section of flesh was removed from her right wrist and forearm. Subject on the table appeared angry and violent. Dr. Sanderson was removed from the room.
At 2:32 p.m., I contacted the other chief medical examiner, Dr. Peter Fong, and asked him how we ought to proceed. Dr. Fong advised close adherence to Statute 50.21 of City Code, and asked me to contact subject's family.
3:15 p.m.: The Egleston family arrived. Two younger brothers (Darryl and Ernest) and the older sister (Pamela) to the subject. At this point, as per my instructions, the body had been restrained by four male nurses, and strapped to the table. Upon seeing their brother lying there, writhing, angry, and snapping at them whenever they tried to go near, the Egleston family signed the papers and determined that the subject's time of death was indeed 12:01 p.m.
At 3:38 p.m., under the watch of the subject's surviving family and Chief Medical Examiner Dr. Peter Fong, myself and Dr. Brewer performed the final immobilization: we used the captive bolt pistol, in accordance with state law for Z-2 sufferers, and placed the nozzle on the right temple of the subject's head. The firing pin penetrated the skull and destroyed the brain. We performed this procedure twice more, from the left temple and from the base of the skull, to make absolutely sure that the subject was not able to move again.
At 3:52 p.m., in accordance with the No-Reanimation Law recently enacted by the POTUS, and the rules and guidelines set down in the U.N. Z-2 Emergency Summit, subject's body was moved to the incinerator without any further public viewing.
Blood and toxicology tests performed on minor necrotic cells and blood samples gathered before Z-2 onset.
Subject began showing signs of Z-1 and Z-2 infection at 12:53 p.m., approximately 52 minutes after death was declared. The body began to show a fever, despite having been dead and cold to the touch for almost an hour. Temperature was taken, showing 109.4 F (43 C), until finally it began to "cool" to around 101.2 F.
Subject's body began twitching at 1:04 p.m., not terribly uncommon in the recently deceased. However, the eyelids opened at 1:27 p.m. and moved about, showing definite signs of awareness. Subject moved his lips, pushed air out from his mouth four times, and reached for Dr. Brewer, feeling of his labcoat, as though he was familiar with the texture. At 1:35 p.m., after generally reaching about at other objects around the table he was laid on, subject suddenly went into convulsions and closed his eyes again. Subject inert at 1:37 p.m.
2:02 p.m.: Z-1 infection has completely morphed into Z-2. Subject's body temperature suddenly plummeted. Within the span of a few minutes, the temperature dropped from 98.6 F (37 C) to around 71.6 F (22 C). Though liver, heart and lungs have all ceased functioning, the eyes have once again opened, and the arms are reaching out, this time not just to Dr. Brewer, but to others in the room, as well.
2:09 p.m.: subject has gone inert again. I enacted Z-ready protocols and advised medical team to maintain a three-foot distance from subject, as Z-2 sufferers are known to be erratic.
At 2:17 p.m., subject suddenly became very animated, and reached out to grab hold of Dr. Sanderson (despite my instructions, Dr. Sanderson chose to examine the subject's eyes). Sanderson was bit; a large section of flesh was removed from her right wrist and forearm. Subject on the table appeared angry and violent. Dr. Sanderson was removed from the room.
At 2:32 p.m., I contacted the other chief medical examiner, Dr. Peter Fong, and asked him how we ought to proceed. Dr. Fong advised close adherence to Statute 50.21 of City Code, and asked me to contact subject's family.
3:15 p.m.: The Egleston family arrived. Two younger brothers (Darryl and Ernest) and the older sister (Pamela) to the subject. At this point, as per my instructions, the body had been restrained by four male nurses, and strapped to the table. Upon seeing their brother lying there, writhing, angry, and snapping at them whenever they tried to go near, the Egleston family signed the papers and determined that the subject's time of death was indeed 12:01 p.m.
At 3:38 p.m., under the watch of the subject's surviving family and Chief Medical Examiner Dr. Peter Fong, myself and Dr. Brewer performed the final immobilization: we used the captive bolt pistol, in accordance with state law for Z-2 sufferers, and placed the nozzle on the right temple of the subject's head. The firing pin penetrated the skull and destroyed the brain. We performed this procedure twice more, from the left temple and from the base of the skull, to make absolutely sure that the subject was not able to move again.
At 3:52 p.m., in accordance with the No-Reanimation Law recently enacted by the POTUS, and the rules and guidelines set down in the U.N. Z-2 Emergency Summit, subject's body was moved to the incinerator without any further public viewing.
Blood and toxicology tests performed on minor necrotic cells and blood samples gathered before Z-2 onset.
TOXICOLOGY
TEST RESULTS
OFFICE
OF CHIEF MEDICAL EXAMINER SUSAN
LUDNER, M.D., DABFP
TOXICOLOGY
LABORATORY SERVICE CHIEF MEDICAL EXAMINER
ATLANTA
CENTRAL TERRY BREWER, PH.D., DABFT
FULTON
COUNTY, ATLANTA CITY CHIEF
TOXICOLOGIST
NAME:
DANIEL WILLIAM EGLESTON PRIORITY: 1
M.E.
CASE NUMBER: 886670T M.E. TOX NUMBER: 7780333T-XX
BLOOD
ETHANOL NEG
URINE
ETHANOL NEG
URINE
COCAINE NEG
URINE
CANNABINOIDS NEG
GASTRIC
CYANIDE NEG
BLOOD
CYANIDE NEG
URINE
CYANIDE NEG
URINE
OPIATES NEG
BLOOD
ABN (HEART) POS FLUOXETINE
2.630 UG/ML
BLOOD
ABN (FEMORAL) POS FLUOXETINE
0.779 UG/ML
URINE
ABN POS FLUOXETINE
0.771 UG/ML
GASTRIC
ABN POS FLUOXETINE
4.100 UG/ML
LIVER
FLUOXETINE POS FLUOXETINE 61.310
UG/ML
BLOOD
ABN (FEMORAL) POS NORFLUOXETINE 0.607
UG/ML
BLOOD
ABN (HEART) POS NORFLUOXETINE 1.850
UG/ML
URINE
ABN POS NORFLUOXETINE
2.260 UG/ML
GASTRIC
ABN POS NORFLUOXETINE
1.077 UG/ML
LIVER
NORFLUOXETINE POS NORFLUOXETINE 48.810 UG/ML
For
INJURIES, INTERNAL EXAMINATION, SPECIMENS, and MICROSCOPIC DESCRIPTIONS, see
page(s) 4-10.
[Dr.
Samuel P. Brice]
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